Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860036 | 0.90 | ALDH1A1 (0.45) | MAPTMAPK1LMNANPSR1L3MBTL1 | |
| SCHEMBL9860062 | 0.90 | ALDH1A1 (0.45) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL9860063 | 0.87 | SLC6A4 (0.42) | MAPTMAPK1LMNANPSR1L3MBTL1 | |
| SCHEMBL740256 | 0.84 | CA12 (0.52) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL806365 | 0.83 | SLC6A4 (0.50) | MEN1KMT2AKDM4EMAPK1LMNA | |
| SCHEMBL9853719 | 0.82 | SLC6A4 (0.44) | MEN1KMT2AKDM4EMAPK1LMNA | |
| SCHEMBL8303786 | 0.81 | ACHE (0.54) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL9860042 | 0.81 | SLC6A4 (0.47) | MEN1KMT2AMAPTRAB9AMAPK1 | |
| SCHEMBL11606863 | 0.80 | MAPT (0.47) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL30970345 | 0.80 | NQO2 (0.47) | KDM4EMAPTRAB9AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024037527-A1 | BTK DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-02-22 | — | — | WO | disclosed |