Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860036 | 0.87 | ALDH1A1 (0.45) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL9860062 | 0.87 | ALDH1A1 (0.45) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL9860063 | 0.84 | SLC6A4 (0.42) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL30760975 | 0.82 | ATM (0.43) | SLC6A4HRH3SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL806365 | 0.80 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3ALDH1A1MAPK1 | |
| SCHEMBL9860042 | 0.78 | SLC6A4 (0.47) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL9860205 | 0.77 | LMNA (0.53) | ALDH1A1MAPK1HPGDNPSR1POLB | |
| SCHEMBL9859653 | 0.77 | HTT (0.46) | SLC6A4SLC6A2SLC6A3ALDH1A1MAPK1 | |
| SCHEMBL2512315 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1CARM1PRMT6POLB | |
| SCHEMBL22966282 | 0.74 | MAPT (0.57) | SLC6A4SLC6A2SLC6A3HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |