Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264706 | 0.89 | — | — | |
| SCHEMBL917236 | 0.82 | HDAC8 (0.56) | HDAC8HDAC6ALDH1A1POLBHPGD | |
| SCHEMBL7056987 | 0.81 | HDAC8 (0.67) | HDAC8HDAC6ALDH1A1POLBHPGD | |
| SCHEMBL23778496 | 0.81 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDRAB9ANPC1 | |
| SCHEMBL28509489 | 0.81 | ALDH1A1 (0.59) | HDAC8HDAC6ALDH1A1HPGDRAB9A | |
| SCHEMBL23368629 | 0.79 | HDAC8 (0.52) | HDAC8HDAC6ALDH1A1POLBHPGD | |
| SCHEMBL7815855 | 0.79 | RAB9A (0.51) | HDAC8HDAC6ALDH1A1POLBHPGD | |
| SCHEMBL23778509 | 0.79 | ALDH1A1 (0.38) | ALDH1A1POLBHPGDLMNA | |
| SCHEMBL28194093 | 0.77 | HDAC8 (0.50) | HDAC8HDAC6ALDH1A1POLBHPGD | |
| SCHEMBL3071864 | 0.75 | HDAC8 (0.48) | HDAC8HDAC6ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969027-B1 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND FRAGRANCES | BEIERSDORF AG (DE) | 2020-10-14 | — | — | EP | disclosed |
| CN-105828798-B | Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prevention and treatment of sensitive skin | 拜尔斯道夫股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-105050575-B | Combination of alkylamidothiazoles and preservatives | 拜尔斯道夫股份有限公司 | 2019-10-01 | — | — | CN | disclosed |
| EP-3176156-B1 | ALKYLAMIDOTHIAZOLES, COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING THEM, AND THEIR USE FOR THE TREATMENT AND PROPHYLAXIS OF UNWANTED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2019-06-12 | — | — | EP | disclosed |
| EP-2968100-B1 | COMBINATION OF ALKYLAMIDOTHIAZOLES AND PRESERVATIVES | BEIERSDORF AG (DE) | 2019-04-10 | — | — | EP | disclosed |
| US-10245252-B2 | Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prophylaxis or treatment of sensitive skin | BEIERSDORF AG (DE) | 2019-04-02 | — | — | US | disclosed |
| US-10245252-B2 | Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prophylaxis or treatment of sensitive skin | BEIERSDORF AG (DE) | 2019-04-02 | — | — | US | disclosed |
| CN-105050664-B | Combination of alkylamidothiazoles and uv-filter substances | 拜尔斯道夫股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| EP-2969028-B1 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND UV FILTER SUBSTANCES | BEIERSDORF AG (DE) | 2018-05-09 | — | — | EP | disclosed |
| EP-3176156-A1 | ALKYLAMIDOTHIAZOLES, COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING THEM, AND THEIR USE FOR THE TREATMENT AND PROPHYLAXIS OF UNWANTED PIGMENTATION OF THE SKIN | Beiersdorf AG (DE) | 2017-06-07 | — | — | EP | disclosed |
| WO-2004065305-A1 | NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE | UNIVERSITY OF DAYTON (US) | 2004-08-05 | — | — | WO | disclosed |
| US-20040104377-A1 | Non-toxic corrosion-protection pigments based on rare earth elements | UNIVERSITY OF DAYTON | 2004-06-03 | — | — | US | disclosed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10245252-B2 | Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prophylaxis or treatment of sensitive skin | CUTA, TYR, AADAC | HDAC8 1037/4885HDAC6 347/4885ALDH1A1 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.