Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 3/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762469 | 0.89 | ALDH1A1 (0.50) | HTTATML3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL30762505 | 0.88 | L3MBTL1 (0.50) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762426 | 0.87 | KMT2A (0.40) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762601 | 0.84 | HTT (0.47) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762411 | 0.81 | HTT (0.54) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762530 | 0.80 | HTT (0.49) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762629 | 0.79 | ALDH1A1 (0.45) | HTTL3MBTL1ALDH1A1MAPK1KMT2A | |
| SCHEMBL30762375 | 0.78 | HTT (0.49) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762588 | 0.77 | KDM4E (0.53) | HTTATML3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL30762409 | 0.76 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |