Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762411 | 0.88 | HTT (0.54) | L3MBTL1HTTATMKDM4EMAPT | |
| SCHEMBL30762620 | 0.85 | KDM4E (0.45) | ARL3MBTL1HTTATMKDM4E | |
| SCHEMBL30762373 | 0.83 | KDM4E (0.46) | ARL3MBTL1HTTATMKDM4E | |
| SCHEMBL30762585 | 0.80 | CNR1 (0.37) | CNR1CNR2ARL3MBTL1HTT | |
| SCHEMBL30762469 | 0.80 | ALDH1A1 (0.50) | CNR1CNR2L3MBTL1HTTATM | |
| SCHEMBL23110352 | 0.79 | L3MBTL1 (0.52) | CNR1CNR2ARL3MBTL1HTT | |
| SCHEMBL23110353 | 0.77 | L3MBTL1 (0.53) | CNR1CNR2L3MBTL1HTTATM | |
| SCHEMBL23110367 | 0.76 | L3MBTL1 (0.52) | CNR1CNR2ARL3MBTL1HTT | |
| SCHEMBL30762689 | 0.76 | PTGES (0.36) | ALDH1A1 | |
| SCHEMBL30762663 | 0.72 | HTT (0.54) | L3MBTL1HTTATMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |