Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762537 | 0.87 | HTT (0.49) | KMT2AMEN1NPC1RAB9ANPSR1 | |
| SCHEMBL30762539 | 0.79 | KMT2A (0.40) | KMT2AMEN1NPC1RAB9AATR | |
| SCHEMBL30762469 | 0.76 | ALDH1A1 (0.50) | KMT2AMEN1NPSR1KDM4EALDH1A1 | |
| SCHEMBL30762505 | 0.75 | L3MBTL1 (0.50) | KMT2AMEN1ATRPKMPIK3C2B | |
| SCHEMBL30808225 | 0.73 | MET (0.47) | KMT2AMEN1NPC1RAB9ANPSR1 | |
| SCHEMBL30762601 | 0.72 | HTT (0.47) | ATRKDM4EALDH1A1HTTLMNA | |
| SCHEMBL30783687 | 0.72 | NPSR1 (0.44) | KMT2AMEN1NPSR1ALDH1A1HPGD | |
| SCHEMBL30784011 | 0.72 | NPSR1 (0.42) | KMT2AMEN1NPC1RAB9ANPSR1 | |
| SCHEMBL30762629 | 0.71 | ALDH1A1 (0.45) | KMT2AMEN1NPSR1KDM4EALDH1A1 | |
| SCHEMBL24312182 | 0.71 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |