Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839139 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10CYP2D6 | |
| SCHEMBL14424527 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10CYP2D6 | |
| SCHEMBL30231784 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10CYP2D6 | |
| SCHEMBL30763269 | 0.81 | CA12 (0.65) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL20839172 | 0.81 | CA12 (0.65) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL12227473 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL14997043 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL30360860 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL26804667 | 0.76 | NOD2 (0.79) | KDM4EALDH1A1HPGDHSD17B10CYP2D6 | |
| SCHEMBL20420764 | 0.75 | AR (0.57) | KDM4EALDH1A1HPGDHSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | disclosed |