Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764707 | 0.83 | HSD11B1 (0.55) | HPGDHSD11B1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30764757 | 0.79 | HSD11B1 (0.46) | HPGDHSD11B1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30764735 | 0.79 | HSD11B1 (0.51) | HSD11B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30764702 | 0.78 | GHSR (0.46) | HSD11B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10899174 | 0.78 | MAPT (0.74) | GAAMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL20304895 | 0.78 | HDAC1 (0.53) | GAAMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL30764715 | 0.76 | HSD11B1 (0.51) | HSD11B1KMT2AMEN1 | |
| SCHEMBL30764719 | 0.76 | SMN1; SMN2 (0.53) | GAAMAPTHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL10900886 | 0.74 | GAA (0.72) | GAAMAPTHPGDKMT2ACHKA | |
| SCHEMBL30764717 | 0.74 | HSD11B1 (0.46) | HSD11B1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |