Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764757 | 0.84 | HSD11B1 (0.46) | GHSRCHRM2HSD11B1FAAHMEN1 | |
| SCHEMBL30764755 | 0.78 | GAA (0.54) | HSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL30764735 | 0.78 | HSD11B1 (0.51) | HSD11B1FAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL30764707 | 0.78 | HSD11B1 (0.55) | HSD11B1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL30764715 | 0.76 | HSD11B1 (0.51) | GHSRCHRM2HSD11B1FAAHMEN1 | |
| SCHEMBL30764758 | 0.75 | KDM4E (0.59) | GHSRCHRM2HSD11B1MEN1KMT2A | |
| SCHEMBL30764763 | 0.74 | HSD11B1 (0.46) | GHSRCHRM2HSD11B1FAAHKMT2A | |
| SCHEMBL30764737 | 0.74 | HSD11B1 (0.46) | GHSRCHRM2HSD11B1PDCD1LG2CD274 | |
| SCHEMBL30764719 | 0.73 | SMN1; SMN2 (0.53) | GHSRCHRM2HSD11B1ALDH1A1 | |
| SCHEMBL30764713 | 0.72 | HSD11B1 (0.47) | GHSRCHRM2HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |