Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 4/20 | 0.44 |
| ▸ | MLNR | O43193 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764707 | 0.85 | HSD11B1 (0.55) | HSD11B1KMT2AMEN1GPR183SIGMAR1 | |
| SCHEMBL30764755 | 0.79 | GAA (0.54) | HSD11B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30764702 | 0.78 | GHSR (0.46) | HSD11B1KMT2AMEN1ALDH1A1FAAH | |
| SCHEMBL30764715 | 0.78 | HSD11B1 (0.51) | HSD11B1KMT2AMEN1GPR183ATM | |
| SCHEMBL30764734 | 0.78 | KMT2A (0.54) | HSD11B1KMT2AMEN1GPR183ATM | |
| SCHEMBL27253361 | 0.77 | HSD11B1 (0.45) | HSD11B1KMT2AMEN1MLNRSIGMAR1 | |
| SCHEMBL30764757 | 0.76 | HSD11B1 (0.46) | HSD11B1KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL30764754 | 0.76 | HSD11B1 (0.46) | HSD11B1KMT2AMEN1SIGMAR1ATM | |
| SCHEMBL30764763 | 0.76 | HSD11B1 (0.46) | HSD11B1KMT2AGPR183FAAH | |
| SCHEMBL30764758 | 0.75 | KDM4E (0.59) | HSD11B1KMT2AMEN1GPR183ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |