Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764724 | 0.88 | HSD11B1 (0.51) | ALDH1A1KDM4EHSD11B1HRH3SMN1; SMN2 | |
| SCHEMBL30764754 | 0.87 | HSD11B1 (0.46) | HSD11B1SIGMAR1CNR1 | |
| SCHEMBL30764743 | 0.84 | MEN1 (0.51) | HSD11B1SMN1; SMN2CNR1 | |
| SCHEMBL30764710 | 0.81 | HSD11B1 (0.45) | ALDH1A1KDM4EPOLBHSD11B1SMN1; SMN2 | |
| SCHEMBL30764734 | 0.81 | KMT2A (0.54) | POLBHSD11B1 | |
| SCHEMBL30764719 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1HSD11B1HRH3SMN1; SMN2SIGMAR1 | |
| SCHEMBL30764736 | 0.79 | HSD11B1 (0.49) | POLBHSD11B1SIGMAR1 | |
| SCHEMBL30764749 | 0.79 | HSD11B1 (0.49) | HSD11B1SIGMAR1TP53MAPT | |
| SCHEMBL30764707 | 0.78 | HSD11B1 (0.55) | ALDH1A1KDM4EHSD11B1SMN1; SMN2SIGMAR1 | |
| SCHEMBL27253461 | 0.75 | MEN1 (0.47) | ALDH1A1KDM4EPOLBHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |