Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764731 | 0.94 | HSD11B1 (0.56) | KMT2AMEN1HSD11B1MCHR1POLB | |
| SCHEMBL30764724 | 0.88 | HSD11B1 (0.51) | KMT2AMEN1HSD11B1KCNJ1KCNH2 | |
| SCHEMBL30764754 | 0.88 | HSD11B1 (0.46) | KMT2AMEN1HSD11B1KCNH2GFER | |
| SCHEMBL30764719 | 0.85 | SMN1; SMN2 (0.53) | HSD11B1 | |
| SCHEMBL30764706 | 0.85 | L3MBTL1 (0.57) | HSD11B1 | |
| SCHEMBL30764756 | 0.84 | HSD11B1 (0.47) | KMT2AMEN1HSD11B1MCHR1POLB | |
| SCHEMBL30764736 | 0.83 | HSD11B1 (0.49) | HSD11B1POLBHTR2A | |
| SCHEMBL30764749 | 0.81 | HSD11B1 (0.49) | KMT2AMEN1HSD11B1GPR183KCNH2 | |
| SCHEMBL30764764 | 0.81 | ALDH1A1 (0.49) | HSD11B1POLB | |
| SCHEMBL30764735 | 0.78 | HSD11B1 (0.51) | KMT2AMEN1HSD11B1GPR183DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |