Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764756 | 0.91 | HSD11B1 (0.47) | HSD11B1KMT2AMEN1KCNH2TP53 | |
| SCHEMBL30764724 | 0.81 | HSD11B1 (0.51) | HSD11B1KMT2AMEN1GFERATM | |
| SCHEMBL30764734 | 0.81 | KMT2A (0.54) | HSD11B1KMT2AMEN1GFERATM | |
| SCHEMBL30764707 | 0.80 | HSD11B1 (0.55) | HSD11B1KMT2AMEN1GFERATM | |
| SCHEMBL30764745 | 0.80 | SIGMAR1 (0.53) | HSD11B1KMT2AMEN1KCNH2CYP2C19 | |
| SCHEMBL30764764 | 0.79 | ALDH1A1 (0.49) | HSD11B1TP53MAPTSIGMAR1 | |
| SCHEMBL30764754 | 0.79 | HSD11B1 (0.46) | HSD11B1KMT2AMEN1GFERATM | |
| SCHEMBL30764719 | 0.78 | SMN1; SMN2 (0.53) | HSD11B1MAPTSIGMAR1 | |
| SCHEMBL30764710 | 0.77 | HSD11B1 (0.45) | HSD11B1KMT2AGFERATMKCNH2 | |
| SCHEMBL30764731 | 0.74 | HSD11B1 (0.56) | HSD11B1KMT2AMEN1KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |