Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764736 | 0.92 | HSD11B1 (0.49) | HSD11B1SLC6A3SIGMAR1 | |
| SCHEMBL30764734 | 0.88 | KMT2A (0.54) | HSD11B1MEN1KMT2AKCNH2GFER | |
| SCHEMBL30764764 | 0.87 | ALDH1A1 (0.49) | HSD11B1CNR1SIGMAR1 | |
| SCHEMBL30764743 | 0.86 | MEN1 (0.51) | HSD11B1MEN1KMT2ACNR1CYP2D6 | |
| SCHEMBL30764731 | 0.81 | HSD11B1 (0.56) | HSD11B1MEN1KMT2AKCNH2 | |
| SCHEMBL30764739 | 0.81 | MEN1 (0.52) | HSD11B1MEN1KMT2ACNR1CYP2D6 | |
| SCHEMBL30764724 | 0.81 | HSD11B1 (0.51) | HSD11B1MEN1KMT2AKCNH2CYP2C19 | |
| SCHEMBL30764749 | 0.79 | HSD11B1 (0.49) | HSD11B1MEN1KMT2ASIGMAR1KCNH2 | |
| SCHEMBL30764719 | 0.78 | SMN1; SMN2 (0.53) | HSD11B1SIGMAR1 | |
| SCHEMBL30764707 | 0.78 | HSD11B1 (0.55) | HSD11B1MEN1KMT2ASIGMAR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |