SCHEMBL30765013

SCHEMBL30765013

O=c1[nH]c(I)c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.44
UMPS P11172 1/20 0.39
TK2 O00142 2/20 0.38
SYNJ2 O15056 1/20 0.38
SLC28A1 O00337 1/20 0.38
SLC28A2 O43868 1/20 0.38
SLC29A1 Q99808 1/20 0.38
SLC28A3 Q9HAS3 1/20 0.38
PNP P00491 2/20 0.37
MGAM O43451 1/20 0.37
GUSB P08236 1/20 0.37
MMP9 P14780 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
ALPI P09923 1/20 0.37
ALPG P10696 1/20 0.37
HPGD P15428 1/20 0.37
APEX1 P27695 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30721680 0.84 UMPS (0.43) UMPSSYNJ2PNPMGAMGUSB
SCHEMBL25319293 0.83 SYNJ2 (0.39) PYGMUMPSSYNJ2MGAMGUSB
SCHEMBL26985063 0.82 UMPS (0.42) UMPSSYNJ2PNPMGAMGUSB
SCHEMBL15810658 0.82 SYNJ2 (0.43) UMPSSYNJ2PNPMGAMGUSB
SCHEMBL19007497 0.82 SYNJ2 (0.43) UMPSSYNJ2PNPMGAMGUSB
SCHEMBL23800771 0.82 SYNJ2 (0.43) PYGMUMPSSYNJ2MGAMGUSB
SCHEMBL30765018 0.82 KDM4E (0.41) PYGMUMPSSYNJ2PNPMGAM
SCHEMBL25317820 0.82 SYNJ2 (0.43) PYGMUMPSSYNJ2MGAMGUSB
SCHEMBL18158986 0.82 SYNJ2 (0.43) UMPSSYNJ2PNPMGAMGUSB
SCHEMBL15798500 0.82 SYNJ2 (0.43) UMPSSYNJ2PNPMGAMGUSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4569112-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING AT ALTERNATIVE SPLICE SITES Remix Therapeutics Inc. (US) 2025-06-18 EP disclosed
WO-2024035952-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING AT ALTERNATIVE SPLICE SITES REMIX THERAPEUTICS INC. (US) 2024-02-15 WO disclosed