SCHEMBL25319293

SCHEMBL25319293

O=c1[nH]c([O-])c([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(=O)[nH]1.[Na+]

nearest known ligand 0.39

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MGAM O43451 1/20 0.38
GUSB P08236 1/20 0.38
MMP9 P14780 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ALPI P09923 1/20 0.38
ALPG P10696 1/20 0.38
HPGD P15428 1/20 0.38
APEX1 P27695 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
UMPS P11172 1/20 0.38
PYGL P06737 3/20 0.37
PYGM P11217 3/20 0.37
B4GALT1 P15291 1/20 0.36
P2RY14 Q15391 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765013 0.83 PYGM (0.44) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL23800771 0.83 SYNJ2 (0.43) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL25317820 0.83 SYNJ2 (0.43) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL31119070 0.82 SYNJ2 (0.43) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL30721680 0.81 UMPS (0.43) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL30765018 0.80 KDM4E (0.41) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL18158986 0.80 SYNJ2 (0.43) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL26985063 0.80 UMPS (0.42) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL15810658 0.80 SYNJ2 (0.43) SYNJ2KDM4EMGAMGUSBMMP9
SCHEMBL15798500 0.80 SYNJ2 (0.43) SYNJ2KDM4EMGAMGUSBMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250108116-A1 GLYCOSYL BARBITURATE-BASED GELLING AGENTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-04-03 US disclosed
EP-4466094-A1 GLYCOSYL BARBITURATE-BASED GELLING AGENTS Centre National de la Recherche Scientifique (FR) 2024-11-27 EP disclosed
WO-2023139217-A1 GLYCOSYL BARBITURATE-BASED GELLING AGENTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250108116-A1 GLYCOSYL BARBITURATE-BASED GELLING AGENTS B3GAT3, GALR3, GABRG3 SYNJ2 4423/4885KDM4E 1836/4885MGAM 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.