SCHEMBL30765018

SCHEMBL30765018

O=c1[nH]c(Cl)c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
LMNA P02545 2/20 0.41
PYGM P11217 2/20 0.41
GMNN O75496 1/20 0.41
MAPT P10636 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
STAT6 P42226 1/20 0.41
HIF1A Q16665 1/20 0.41
UMPS P11172 1/20 0.39
SLC5A2 P31639 1/20 0.39
SYNJ2 O15056 1/20 0.38
PNP P00491 2/20 0.37
HPGD P15428 2/20 0.37
MGAM O43451 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30721680 0.84 UMPS (0.43) KDM4ELMNACYP1A2TSHRUMPS
SCHEMBL15798500 0.82 SYNJ2 (0.43) KDM4ELMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL26985063 0.82 UMPS (0.42) KDM4ELMNAUMPSSYNJ2PNP
SCHEMBL19007497 0.82 SYNJ2 (0.43) KDM4ELMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL23800771 0.82 SYNJ2 (0.43) KDM4EPYGMMAPTCYP1A2UMPS
SCHEMBL25317820 0.82 SYNJ2 (0.43) KDM4EPYGMMAPTCYP1A2UMPS
SCHEMBL30765013 0.82 PYGM (0.44) KDM4ELMNAPYGMUMPSSYNJ2
SCHEMBL18158986 0.82 SYNJ2 (0.43) KDM4ELMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL15810658 0.82 SYNJ2 (0.43) KDM4ELMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL31119070 0.81 SYNJ2 (0.43) KDM4EPYGMMAPTCYP1A2UMPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4569112-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING AT ALTERNATIVE SPLICE SITES Remix Therapeutics Inc. (US) 2025-06-18 EP disclosed
WO-2024035952-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING AT ALTERNATIVE SPLICE SITES REMIX THERAPEUTICS INC. (US) 2024-02-15 WO disclosed