Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805576 | 1.00 | CES2 (0.39) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3101770 | 0.87 | NOTUM (0.37) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL488779 | 0.87 | DPP4 (0.38) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL30553986 | 0.87 | DPP4 (0.38) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL30313251 | 0.85 | KMT2A (0.40) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL714300 | 0.85 | KMT2A (0.40) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8262561 | 0.81 | RAB9A (0.42) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL3113530 | 0.80 | CES2 (0.38) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2334297 | 0.79 | DPP4 (0.41) | CES2CES1SMN1; SMN2P2RX7ALDH2 | |
| SCHEMBL1165021 | 0.79 | ALDH1A1 (0.44) | CES2CES1P2RX7ALDH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |