Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 5/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 4/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765553 | 0.88 | MAPK1 (0.37) | F2MAPK1NTRK1NTRK3F3 | |
| SCHEMBL30766040 | 0.86 | F2 (0.36) | F2MAPK1NTRK1NTRK3F3 | |
| SCHEMBL30765657 | 0.83 | F2 (0.36) | F2MAPK1NTRK1NTRK3F3 | |
| SCHEMBL30765781 | 0.83 | F2 (0.33) | F2MAPK1F3NAMPTTSHR | |
| SCHEMBL30765646 | 0.82 | MAPK1 (0.38) | F2MAPK1F3MASP2NAMPT | |
| SCHEMBL30765445 | 0.82 | AKT1 (0.37) | GSK3AAKT1AKT2AKT3USP2 | |
| SCHEMBL31558527 | 0.81 | AKT1 (0.36) | MAPK1F7AKT1AKT2AKT3 | |
| SCHEMBL30765998 | 0.78 | ALDH1A1 (0.35) | F2AKT1AKT2AKT3TSHR | |
| SCHEMBL30765806 | 0.77 | MAPK1 (0.36) | F2MAPK1MASP2NAMPTUSP2 | |
| SCHEMBL30765621 | 0.77 | GAA (0.42) | MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |