Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.37 |
| ▸ | AKT2 | P31751 | 6/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558527 | 0.93 | AKT1 (0.36) | AKT1AKT2AKT3ALDH1A1PHGDH | |
| SCHEMBL30765998 | 0.90 | ALDH1A1 (0.35) | AKT1AKT2AKT3ALDH1A1PHGDH | |
| SCHEMBL30765621 | 0.88 | GAA (0.42) | ALDH1A1TSHRLMNAMAPTNPSR1 | |
| SCHEMBL30766001 | 0.82 | AKT1 (0.36) | AKT1AKT2AKT3ALDH1A1PHGDH | |
| SCHEMBL30765435 | 0.82 | F2 (0.36) | AKT1AKT2AKT3IDH1TSHR | |
| SCHEMBL30765622 | 0.80 | IDH1 (0.38) | AKT1AKT2AKT3ALDH1A1PHGDH | |
| SCHEMBL30765713 | 0.79 | AKT1 (0.36) | AKT1AKT2AKT3ALDH1A1IDH1 | |
| SCHEMBL30765827 | 0.79 | AKT1 (0.36) | AKT1AKT2AKT3ALDH1A1IDH1 | |
| SCHEMBL30765552 | 0.78 | LMNA (0.38) | ALDH1A1LMNAPIK3CAKDM4EL3MBTL1 | |
| SCHEMBL31558437 | 0.76 | AKT1 (0.35) | AKT1AKT2AKT3ALDH1A1PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |