Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.36 |
| ▸ | AKT2 | P31751 | 6/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765827 | 1.00 | AKT1 (0.36) | AKT1AKT2AKT3ALDH1A1IDH1 | |
| SCHEMBL30766059 | 0.90 | ALDH1A1 (0.33) | AKT1AKT2AKT3ALDH1A1IDH1 | |
| SCHEMBL30765616 | 0.88 | LMNA (0.37) | AKT1AKT2AKT3ALDH1A1TP53 | |
| SCHEMBL30765781 | 0.83 | F2 (0.33) | TSHR | |
| SCHEMBL30765552 | 0.82 | LMNA (0.38) | ALDH1A1PIK3CADPP4LMNAKDM4E | |
| SCHEMBL30765747 | 0.81 | ELANE (0.39) | ALDH1A1KDM4EMAPT | |
| SCHEMBL30765486 | 0.80 | NTRK1 (0.33) | ALDH1A1 | |
| SCHEMBL30765445 | 0.79 | AKT1 (0.37) | AKT1AKT2AKT3ALDH1A1IDH1 | |
| SCHEMBL30766001 | 0.77 | AKT1 (0.36) | AKT1AKT2AKT3ALDH1A1IDH1 | |
| SCHEMBL30765622 | 0.73 | IDH1 (0.38) | AKT1AKT2AKT3ALDH1A1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |