Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30766096 | 0.76 | RAB9A (0.45) | TP53SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30765787 | 0.75 | CASP1 (0.44) | SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL30765956 | 0.75 | CASP1 (0.41) | TP53SMN1; SMN2MAPTRXFP1KDM4E | |
| SCHEMBL31752304 | 0.69 | ELANE (0.46) | TP53MAPTHPGDPRSS12ESRRG | |
| SCHEMBL30765704 | 0.68 | KDM4E (0.43) | TP53SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30765794 | 0.67 | HDAC1 (0.46) | SMN1; SMN2KDM4EALDH1A1HDAC1WNT3A | |
| SCHEMBL8791232 | 0.67 | NPC1 (0.61) | TP53SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL23460591 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1 | |
| SCHEMBL30765683 | 0.67 | TUBB4A (0.47) | SMN1; SMN2KDM4EHDAC1WNT3AHDAC3 | |
| SCHEMBL30765492 | 0.67 | ELANE (0.49) | SMN1; SMN2KDM4EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |