Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | LATS1 | O95835 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27149698 | 0.76 | NAMPT (0.42) | NAMPTLATS1CYP3A4LATS2L3MBTL1 | |
| SCHEMBL38662549 | 0.76 | LATS1 (0.44) | NAMPTLATS1CYP3A4LATS2L3MBTL1 | |
| SCHEMBL17790284 | 0.73 | BTK (0.39) | CYP3A4SCN9AGPR119GABRG2GABRB3 | |
| SCHEMBL27140815 | 0.73 | NAMPT (0.42) | NAMPTLATS1CYP3A4LATS2L3MBTL1 | |
| SCHEMBL23478372 | 0.72 | NAMPT (0.43) | NAMPTLATS1CYP3A4LATS2CA12 | |
| SCHEMBL31558589 | 0.72 | NAMPT (0.43) | NAMPTLATS1CYP3A4LATS2CA12 | |
| SCHEMBL29773883 | 0.71 | CHRM2 (0.49) | L3MBTL1GPR119GABRG2GABRB3GABRA5 | |
| SCHEMBL3889015 | 0.70 | HTR6 (0.46) | LATS1CYP3A4LATS2L3MBTL1LMNA | |
| SCHEMBL31751595 | 0.68 | NAMPT (0.43) | NAMPTLATS1CYP3A4LATS2KDM4E | |
| SCHEMBL16637537 | 0.68 | GABRG2 (0.37) | NAMPTLATS1GPR119GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |