Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651623 | 1.00 | NR4A2 (0.55) | NR4A2SLC6A3SLC6A4EGFRMAPT | |
| SCHEMBL2941745 | 0.88 | SLC6A3 (0.57) | NR4A2SLC6A3SLC6A4MAPTCYP1A2 | |
| SCHEMBL9143243 | 0.87 | CA12 (0.54) | NR4A2SLC6A3SLC6A4ALDH1A1GAA | |
| SCHEMBL22319386 | 0.87 | NR4A2 (0.55) | NR4A2SLC6A3SLC6A4EGFRMAPT | |
| SCHEMBL38655411 | 0.85 | GAA (0.54) | NR4A2SLC6A3SLC6A4MAPTALDH1A1 | |
| SCHEMBL2296342 | 0.85 | KDM4E (0.58) | MAPTCYP1A2CYP2C19ABCB1ALDH1A1 | |
| SCHEMBL14252250 | 0.84 | NR4A2 (0.59) | NR4A2SLC6A3SLC6A4EGFRMAPT | |
| SCHEMBL70440 | 0.84 | NR4A2 (0.59) | NR4A2SLC6A3SLC6A4EGFRMAPT | |
| SCHEMBL16609019 | 0.83 | LMNA (0.51) | SLC6A3SLC6A4GAAKDM4ELMNA | |
| SCHEMBL17996053 | 0.83 | CFTR (0.47) | SLC6A3SLC6A4EGFRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |