Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558585 | 0.91 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EELANEJAK2 | |
| SCHEMBL30765975 | 0.91 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EELANEJAK2 | |
| SCHEMBL30765722 | 0.87 | ELANE (0.35) | ALDH1A1HPGDKDM4EELANEJAK2 | |
| SCHEMBL30765701 | 0.84 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EELANEJAK2 | |
| SCHEMBL30765963 | 0.81 | GABRP (0.37) | ALDH1A1HPGDKDM4EELANEJAK2 | |
| SCHEMBL30765662 | 0.79 | LMNA (0.34) | ALDH1A1HPGDELANEHSP90AA1HSP90AB1 | |
| SCHEMBL30765536 | 0.79 | LMNA (0.34) | ALDH1A1HPGDELANEHSP90AA1HSP90AB1 | |
| SCHEMBL31558526 | 0.79 | LMNA (0.34) | ALDH1A1HPGDELANEHSP90AA1HSP90AB1 | |
| SCHEMBL30765800 | 0.79 | GAA (0.40) | ALDH1A1HPGDRXFP1HSP90AA1GABRP | |
| SCHEMBL30765703 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |