Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765839 | 0.83 | MEN1 (0.49) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30765661 | 0.80 | MEN1 (0.48) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30766020 | 0.78 | MEN1 (0.46) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30765447 | 0.76 | L3MBTL1 (0.65) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30765514 | 0.76 | ALDH1A1 (0.48) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30766019 | 0.74 | LMNA (0.54) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30765592 | 0.73 | L3MBTL1 (0.50) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30766038 | 0.70 | KMT2A (0.50) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL6649823 | 0.67 | MEN1 (0.44) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL3649935 | 0.66 | KMT2A (0.48) | MEN1KMT2ALMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |