Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765514 | 0.89 | ALDH1A1 (0.48) | LMNATSHRSMN1; SMN2NPC1MAPT | |
| SCHEMBL30765839 | 0.78 | MEN1 (0.49) | LMNATSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30765661 | 0.77 | MEN1 (0.48) | LMNATSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30766142 | 0.76 | HDAC6 (0.40) | LMNATSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30765999 | 0.75 | PDE4B (0.44) | LMNATSHRMAPTKMT2AMEN1 | |
| SCHEMBL30766020 | 0.75 | MEN1 (0.46) | LMNATSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30765740 | 0.74 | MEN1 (0.45) | LMNATSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30765447 | 0.73 | L3MBTL1 (0.65) | LMNATSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30765592 | 0.70 | L3MBTL1 (0.50) | LMNATSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL12120129 | 0.69 | LMNA (0.59) | LMNATSHRSMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |