Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765762 | 0.89 | ALDH1A1 (0.42) | ALDH1A1LMNAGLATSHRMAPK1 | |
| SCHEMBL30765989 | 0.80 | KDM4E (0.51) | ALDH1A1LMNAGLATSHRSMN1; SMN2 | |
| SCHEMBL30765599 | 0.72 | CTRC (0.54) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30765438 | 0.72 | KDM4E (0.50) | ALDH1A1LMNAGLATSHRSMN1; SMN2 | |
| SCHEMBL30765727 | 0.69 | KDM4E (0.44) | ALDH1A1LMNAGLATSHRSMN1; SMN2 | |
| SCHEMBL31558529 | 0.68 | F10 (0.34) | ALDH1A1LMNAGLATSHRMAPK1 | |
| SCHEMBL30765677 | 0.66 | KDM4E (0.49) | ALDH1A1GLAALOX15KDM4ECYP1A2 | |
| SCHEMBL17332419 | 0.66 | NPC1 (0.51) | ALDH1A1LMNAGLANPSR1SMN1; SMN2 | |
| SCHEMBL31750637 | 0.64 | CYP1A2 (0.54) | ALDH1A1LMNAGLATSHRSMN1; SMN2 | |
| SCHEMBL30765794 | 0.64 | HDAC1 (0.46) | ALDH1A1GLASMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |