Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 5/20 | 0.37 |
| ▸ | CTRC | Q99895 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765548 | 0.83 | F2 (0.39) | CMA1CTRCCASP1TSHRAVPR1B | |
| SCHEMBL30765579 | 0.82 | F3 (0.39) | NTRK1NTRK3CMA1CTRCCASP1 | |
| SCHEMBL30765838 | 0.81 | CASP1 (0.41) | CMA1CTRCCASP1ELANEPOLB | |
| SCHEMBL30765764 | 0.81 | CMA1 (0.40) | CMA1CTRC | |
| SCHEMBL30765898 | 0.81 | ITGB3 (0.35) | CMA1CTRCCASP1TSHRAVPR1B | |
| SCHEMBL30765987 | 0.79 | F2 (0.37) | NTRK1CMA1CTRCCASP1MASP2 | |
| SCHEMBL30765494 | 0.79 | F3 (0.34) | CMA1CTRCCASP1TSHRF2 | |
| SCHEMBL30765788 | 0.78 | NTRK1 (0.38) | NTRK1CMA1CTRCPOLB | |
| SCHEMBL30765926 | 0.74 | GAA (0.52) | CASP1AVPR1BELANEPOLB | |
| SCHEMBL30765465 | 0.73 | LMNA (0.39) | CASP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |