Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12636575 | 0.86 | FPR2 (0.46) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL21539717 | 0.80 | LMNA (0.45) | LMNAMEN1KMT2ACNR1L3MBTL1 | |
| SCHEMBL23885502 | 0.79 | LMNA (0.45) | LMNAMEN1KMT2ACNR1L3MBTL1 | |
| SCHEMBL27947806 | 0.76 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL22356899 | 0.74 | LMNA (0.41) | LMNAMEN1KMT2ACNR1L3MBTL1 | |
| SCHEMBL23885633 | 0.74 | LMNA (0.45) | LMNAMEN1KMT2ACNR1L3MBTL1 | |
| SCHEMBL30254395 | 0.74 | LMNA (0.45) | LMNAMEN1KMT2ACNR1L3MBTL1 | |
| SCHEMBL11250299 | 0.72 | KMT2A (0.36) | LMNAKMT2AL3MBTL1GAAALDH1A1 | |
| SCHEMBL30254206 | 0.72 | P2RX7 (0.53) | LMNAMEN1KMT2ACNR1TSHR | |
| SCHEMBL12636573 | 0.71 | FPR2 (0.46) | LMNAMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |