Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765575 | 0.90 | AVPR1B (0.35) | KMT2AAVPR1BMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL30765898 | 0.83 | ITGB3 (0.35) | KMT2AELANEAVPR1BCASP1F2 | |
| SCHEMBL30765769 | 0.76 | NTRK1 (0.40) | ELANEAVPR1BCASP1F2CMA1 | |
| SCHEMBL30765838 | 0.75 | CASP1 (0.41) | ELANECASP1HDAC6CMA1CTRC | |
| SCHEMBL30765548 | 0.72 | F2 (0.39) | KMT2AELANEAVPR1BCASP1F2 | |
| SCHEMBL30765784 | 0.71 | NPSR1 (0.35) | KMT2AELANECASP1MEN1ALDH1A1 | |
| SCHEMBL30765442 | 0.71 | ELANE (0.38) | KMT2AELANEMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL30765948 | 0.71 | LMNA (0.39) | ELANECMA1CTRC | |
| SCHEMBL23460845 | 0.71 | F2 (0.45) | P2RX3F2 | |
| SCHEMBL30765926 | 0.71 | GAA (0.52) | KMT2AELANEAVPR1BCASP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |