Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765622 | 0.87 | IDH1 (0.38) | ALDH1A1NPSR1IDH1NPC1ELANE | |
| SCHEMBL30765475 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1TSHRNPSR1KDM4E | |
| SCHEMBL31558496 | 0.86 | IDH1 (0.37) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL30765811 | 0.84 | L3MBTL1 (0.41) | MAPTPOLBL3MBTL1GAAKMT2A | |
| SCHEMBL30765621 | 0.83 | GAA (0.42) | MAPTPOLBL3MBTL1GAAKMT2A | |
| SCHEMBL30766040 | 0.77 | F2 (0.36) | MAPK1IDH1 | |
| SCHEMBL30765509 | 0.76 | LMNA (0.43) | MAPTPOLBL3MBTL1GAAKMT2A | |
| SCHEMBL30765616 | 0.76 | LMNA (0.37) | MAPTPOLBL3MBTL1GAAKMT2A | |
| SCHEMBL30765532 | 0.73 | GAA (0.53) | MAPTPOLBL3MBTL1GAAKMT2A | |
| SCHEMBL30765514 | 0.72 | ALDH1A1 (0.48) | MAPTPOLBL3MBTL1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |