Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 4/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767766 | 1.00 | KMT2A (0.42) | KMT2ASCN4ARXRARXRBRXRG | |
| SCHEMBL21174417 | 0.80 | BRD4 (0.39) | RXRARXRBRXRGKDM4EPTGDR2 | |
| SCHEMBL4433133 | 0.75 | MET (0.48) | RXRARXRBRXRGMKNK1MKNK2 | |
| SCHEMBL30767774 | 0.72 | RXRA (0.56) | KMT2ARXRARXRBRXRGALDH1A1 | |
| SCHEMBL8512 | 0.71 | AKR1B1 (0.48) | KMT2ARXRARXRBRXRGKDM4E | |
| SCHEMBL13861301 | 0.70 | RIPK1 (0.52) | — | |
| SCHEMBL23559593 | 0.70 | KDM4E (0.48) | KMT2ASCN4AJMJD6MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL3297493 | 0.69 | AKR1B1 (0.46) | KMT2ARXRARXRBRXRGKDM4E | |
| SCHEMBL31716086 | 0.68 | LDHA (0.51) | RXRARXRBRXRGKDM4EPTGDR2 | |
| SCHEMBL24378466 | 0.67 | KMT2A (0.60) | KMT2ASCN4ACYP19A1KEAP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014851-A1 | NOVEL PURINE DERIVATIVE COMPOUNDS AS HIF-1 PROTEIN INHIBITOR | 주식회사 넥스트젠바이오사이언스 | 2024-01-18 | — | — | WO | disclosed |