Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.43 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29160425 | 1.00 | MAOA (0.43) | MAOAMAOBFTOACHESIGMAR1 | |
| SCHEMBL32670130 | 0.82 | NPC1 (0.50) | MAOAMAOBFTOACHESIGMAR1 | |
| SCHEMBL6620745 | 0.80 | TTR (0.51) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL30768028 | 0.80 | TTR (0.51) | MAOAMAOBFTOACHEDYRK1A | |
| SCHEMBL827356 | 0.79 | CTNNB1 (0.55) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1874005 | 0.79 | HTR1A (0.51) | MAOAMAOBFTOACHESIGMAR1 | |
| SCHEMBL30768023 | 0.79 | HTR1A (0.51) | MAOAMAOBFTOACHESIGMAR1 | |
| SCHEMBL30768009 | 0.78 | NQO2 (0.50) | MAOAMAOBFTOACHESIGMAR1 | |
| SCHEMBL30768058 | 0.78 | NQO2 (0.50) | MAOAMAOBFTOACHESIGMAR1 | |
| SCHEMBL827802 | 0.76 | HTR1B (0.55) | MAOAACHEDYRK1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117615763-A | Phosphoinositide 3 kinase beta inhibitor, composition and preparation method thereof | 健道生物医药有限公司 | 2024-02-27 | — | — | CN | disclosed |