Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699335 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHTTNPC1NR2F2 | |
| SCHEMBL28697181 | 0.84 | LMNA (0.46) | SMN1; SMN2LMNAHTTNPC1NR2F2 | |
| SCHEMBL22747792 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHTTNPC1NR2F2 | |
| SCHEMBL28702756 | 0.81 | LMNA (0.48) | SMN1; SMN2LMNAHTTNPC1NR2F2 | |
| SCHEMBL2142144 | 0.79 | MAPT (0.42) | SMN1; SMN2LMNAHTTMAPTALDH1A1 | |
| SCHEMBL28682374 | 0.78 | GPR119 (0.45) | SMN1; SMN2LMNAHTTNPC1NR2F2 | |
| SCHEMBL2128838 | 0.78 | MAPT (0.43) | SMN1; SMN2LMNAHTTMAPTALDH1A1 | |
| SCHEMBL28932211 | 0.77 | LMNA (0.48) | SMN1; SMN2LMNAHTTNPC1NR2F2 | |
| SCHEMBL2143583 | 0.76 | PDK2 (0.40) | SMN1; SMN2LMNAHTTMAPTALDH1A1 | |
| SCHEMBL28903414 | 0.76 | MAPT (0.46) | SMN1; SMN2LMNAHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874354-B | Pyridone derivative, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-02-20 | — | — | CN | disclosed |