Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 12/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965537 | 0.94 | SCD5 (0.44) | USP2HSD17B10CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30831067 | 0.94 | HSD17B10 (0.51) | USP2HSD17B10CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL25034770 | 0.93 | GPR119 (0.50) | ALDH1A1GPR119KIT | |
| SCHEMBL30830960 | 0.93 | GPR119 (0.50) | ALDH1A1GPR119KIT | |
| SCHEMBL30830495 | 0.91 | GPR119 (0.47) | USP2HSD17B10CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30830897 | 0.89 | GPR119 (0.45) | USP2HSD17B10CYP3A4MAPK1CYP2C19 | |
| SCHEMBL30830759 | 0.89 | HSD17B10 (0.40) | USP2HSD17B10CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30830964 | 0.88 | GPR119 (0.44) | USP2HSD17B10CYP3A4MAPK1CYP2C19 | |
| SCHEMBL30830492 | 0.88 | GPR119 (0.44) | USP2HSD17B10CYP3A4MAPK1CYP2C19 | |
| SCHEMBL30830739 | 0.87 | PARP1 (0.42) | GPR119KITSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |