Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | EPOR | P19235 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682322 | 0.80 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL15973261 | 0.80 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL15973260 | 0.80 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL19696089 | 0.80 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL19175806 | 0.80 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL30769418 | 0.79 | PTGES (0.47) | KMT2ASMN1; SMN2PTGESFFAR1LTA4H | |
| SCHEMBL2853880 | 0.78 | ALOX5 (0.63) | KMT2ASMN1; SMN2ALOX5PTGESLTA4H | |
| SCHEMBL2847366 | 0.76 | KMT2A (0.51) | KMT2ASMN1; SMN2ALOX5PTGESFFAR1 | |
| SCHEMBL9432429 | 0.76 | KMT2A (0.59) | KMT2ASMN1; SMN2ALOX5LTA4HMEN1 | |
| SCHEMBL9019941 | 0.76 | KMT2A (0.59) | KMT2ASMN1; SMN2ALOX5LTA4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |