Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297104 | 1.00 | MAOA (0.40) | MAOAMAOBMAPKAPK2DRD1 | |
| SCHEMBL28660534 | 0.89 | MAOA (0.40) | MAOAMAOBMAPKAPK2DRD1 | |
| SCHEMBL28904464 | 0.82 | NPSR1 (0.32) | MAOAMAOB | |
| SCHEMBL6698583 | 0.77 | MAOA (0.52) | MAOAMAOBMAPKAPK2 | |
| SCHEMBL6599502 | 0.77 | MAOA (0.42) | MAOAMAOBMAPKAPK2 | |
| SCHEMBL6599506 | 0.72 | MAOA (0.43) | MAOAMAOBMAPKAPK2DRD1 | |
| SCHEMBL30168142 | 0.71 | MAOA (0.46) | MAOAMAOBMAPKAPK2DRD1 | |
| SCHEMBL2658102 | 0.71 | MAOA (0.46) | MAOAMAOBMAPKAPK2DRD1 | |
| SCHEMBL31673358 | 0.69 | MAOA (0.50) | MAOAMAOBDRD1 | |
| SCHEMBL115187 | 0.69 | MAOA (0.50) | MAOAMAOBMAPKAPK2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427412-B | Nitrogen-containing fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-02-20 | — | — | CN | disclosed |