Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30773945 | 0.90 | HRH3 (0.41) | GPR142SLC22A6SLC22A8SLC22A12FAAH | |
| SCHEMBL30774039 | 0.88 | GPR142 (0.53) | GPR142ROCK2FAAHNAAAROCK1 | |
| SCHEMBL1191643 | 0.77 | SLC22A12 (0.55) | SLC22A6SLC22A8SLC22A12FAAHNAAA | |
| SCHEMBL28630081 | 0.74 | DGAT1 (0.45) | GPR142OPRD1FAAHNAAAHRH3 | |
| SCHEMBL30774782 | 0.73 | MAPT (0.50) | ROCK2ME2ME1ME3 | |
| SCHEMBL1190940 | 0.73 | HSD17B10 (0.51) | ROCK2SLC22A6SLC22A8SLC22A12FAAH | |
| SCHEMBL28615356 | 0.71 | CNR1 (0.49) | FAAHHRH3RIPK1CNR1HIF1A | |
| SCHEMBL30774594 | 0.71 | STAT3 (0.42) | GPR142SLC22A12FAAHNAAAROCK1 | |
| SCHEMBL1191269 | 0.69 | SLC22A12 (0.72) | SLC22A6SLC22A8SLC22A12FAAHNAAA | |
| SCHEMBL30774767 | 0.67 | SLC22A6 (0.51) | SLC22A6SLC22A8SLC22A12NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024061371-A1 | ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州威诺森医药科技有限公司 | 2024-03-28 | — | — | WO | claimed |
| WO-2024061371-A1 | ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州威诺森医药科技有限公司 | 2024-03-28 | — | — | WO | disclosed |