SCHEMBL30774556

SCHEMBL30774556

N#Cc1ccc(-c2cncc3c2CCN3C(=O)c2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ UCHL1 P09936 1/20 0.46
▸ USP30 Q70CQ3 1/20 0.46
▸ VNN1 O95497 1/20 0.43
▸ PDCD1 Q15116 11/20 0.43
▸ CD274 Q9NZQ7 11/20 0.43
▸ KDM1A O60341 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ELANE P08246 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ SAE1 Q9UBE0 1/20 0.41
▸ UBA2 Q9UBT2 1/20 0.41
▸ RAF1 P04049 1/20 0.41
▸ BRAF P15056 1/20 0.41
▸ ABL1 P00519 1/20 0.40
▸ BCR P11274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774543 0.89 USP30 (0.49) UCHL1USP30PDCD1CD274
SCHEMBL30774581 0.89 GAA (0.48) UCHL1USP30PDCD1CD274MAPT
SCHEMBL30774411 0.88 KDM1A (0.47) UCHL1USP30PDCD1CD274KDM1A
SCHEMBL30774520 0.87 USP30 (0.47) UCHL1USP30PDCD1CD274ELANE
SCHEMBL30774494 0.87 UCHL1 (0.47) UCHL1USP30PDCD1CD274
SCHEMBL30773976 0.85 VNN1 (0.41) UCHL1USP30VNN1KDM1ALMNA
SCHEMBL30774021 0.85 VNN1 (0.41) UCHL1USP30VNN1KDM1ALMNA
SCHEMBL30774363 0.85 CYP11B2 (0.55) UCHL1USP30PDCD1CD274MAPT
SCHEMBL30774625 0.85 USP30 (0.49) UCHL1USP30PDCD1CD274
SCHEMBL30774867 0.84 STAT3 (0.52) UCHL1USP30PDCD1CD274POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 UCHL1 1728/4885USP30 728/4885VNN1 4452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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