SCHEMBL30773976

SCHEMBL30773976

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)c2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ VNN1 O95497 2/20 0.41
▸ KDM1A O60341 1/20 0.40
▸ RAF1 P04049 5/20 0.40
▸ BRAF P15056 5/20 0.40
▸ LMNA P02545 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ SAE1 Q9UBE0 1/20 0.39
▸ UBA2 Q9UBT2 1/20 0.39
▸ ABL1 P00519 2/20 0.38
▸ BCR P11274 2/20 0.38
▸ ELANE P08246 1/20 0.37
▸ STAT3 P40763 1/20 0.37
▸ CCR2 P41597 1/20 0.36
▸ PTGDR2 Q9Y5Y4 1/20 0.36
▸ UCHL1 P09936 2/20 0.36
▸ USP30 Q70CQ3 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30773968 0.89 KDM1A (0.44) VNN1KDM1ASTAT3PTGDR2
SCHEMBL30774894 0.88 CYP3A4 (0.42) HPGDMAPTABL1BCRUCHL1
SCHEMBL30774926 0.86 KCNH2 (0.43) POLBUCHL1USP30
SCHEMBL30774556 0.85 UCHL1 (0.46) VNN1KDM1ARAF1BRAFLMNA
SCHEMBL30774563 0.85 GPR142 (0.46) VNN1PTGDR2
SCHEMBL30774484 0.85 CYP11B2 (0.48) MAPTABL1BCR
SCHEMBL30774506 0.84 STAT3 (0.44) KDM1APOLBMAPTSTAT3UCHL1
SCHEMBL30774934 0.83 KDM4E (0.43) KDM1ALMNAKDM4EMAPTELANE
SCHEMBL30774021 0.82 VNN1 (0.41) VNN1KDM1ARAF1BRAFLMNA
SCHEMBL30774812 0.82 CYP11B2 (0.42) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 VNN1 4452/4885KDM1A 621/4885RAF1 1231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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