Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30931623 | 0.76 | LOXL2 (0.40) | CYP11B1CYP11B2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL3359088 | 0.73 | HRH4 (0.40) | L3MBTL1MAPTALDH1A1THRBKDM4E | |
| SCHEMBL29560184 | 0.73 | HRH4 (0.40) | L3MBTL1MAPTALDH1A1THRBKDM4E | |
| SCHEMBL30896160 | 0.71 | ALDH1A1 (0.43) | CYP11B1CYP11B2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL2461154 | 0.70 | L3MBTL1 (0.56) | L3MBTL1GABRA5MAPTALDH1A1THRB | |
| SCHEMBL24517539 | 0.70 | — | — | |
| SCHEMBL651977 | 0.69 | ALDH1A1 (0.44) | CYP11B1CYP11B2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL13259534 | 0.69 | NT5E (0.34) | CYP11B1CYP11B2KDM4E | |
| SCHEMBL22518704 | 0.68 | L3MBTL1 (0.45) | L3MBTL1MAPTALDH1A1THRBKDM4E | |
| SCHEMBL15709845 | 0.68 | AMD1 (0.37) | L3MBTL1MAPTALDH1A1THRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568746-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |