Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.68 |
| ▸ | RAB9A | P51151 | 11/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.68 |
| ▸ | RELA | Q04206 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077797 | 1.00 | NPC1 (0.68) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL27912466 | 0.85 | NPC1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL14482456 | 0.83 | MGLL (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3079233 | 0.83 | NPC1 (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3079231 | 0.83 | NPC1 (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3070581 | 0.83 | NPC1 (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3057246 | 0.81 | MMP1 (0.61) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL19657986 | 0.81 | NPC1 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3057250 | 0.81 | MMP1 (0.61) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL16218028 | 0.81 | NPC1 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833331-B2 | Non-toxic corrosion-protection pigments based on cobalt | UNIVERSITY OF DAYTON (US) | 2010-11-16 | — | — | US | disclosed |
| US-7789958-B2 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090163628-A1 | NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT | STURGILL JEFFREY ALLEN | 2009-06-25 | — | — | US | disclosed |
| US-7422793-B2 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | UNIVERSITY OF DAYTON (US) | 2008-09-09 | — | — | US | disclosed |
| US-7407711-B2 | Non-toxic corrosion-protection conversion coats based on rare earth elements | UNIVERSITY OF DAYTON (US) | 2008-08-05 | — | — | US | disclosed |
| US-20080161575-A1 | Process for the synthesis of 6-amino-4-(3-chloro-4-fluorophenylamino)-7-ethoxyquinoline-3-carbonitrile | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
| US-7365203-B2 | Process for the synthesis of 6-amino-4-(3-chloro-4-fluoro-phenylamino)-7-ethoxy-quinoline-3-carbonitrile | WYETH (US) | 2008-04-29 | — | — | US | disclosed |
| US-20080033175-A1 | Process for preparation of 4-amino-3-quinolinecarbonitriles | WYETH HOLDINGS CORPORATION (US) | 2008-02-07 | — | — | US | disclosed |
| US-7297795-B2 | Process for preparation of 4-amino-3-quinolinecarbonitriles | WYETH HOLDINGS CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |
| US-7294211-B2 | Non-toxic corrosion-protection conversion coats based on cobalt | UNIVERSITY OF DAYTON (US) | 2007-11-13 | — | — | US | disclosed |
| US-20040204587-A1 | Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolones | WYETH HOLDINGS CORPORATION | 2004-10-14 | — | — | US | disclosed |
| WO-2004065305-A1 | NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE | UNIVERSITY OF DAYTON (US) | 2004-08-05 | — | — | WO | disclosed |
| US-20040104377-A1 | Non-toxic corrosion-protection pigments based on rare earth elements | UNIVERSITY OF DAYTON | 2004-06-03 | — | — | US | disclosed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161575-A1 | Process for the synthesis of 6-amino-4-(3-chloro-4-fluorophenylamino)-7-ethoxyquinoline-3-carbonitrile | QPCT, CYP3A4, CPNE4 | NPC1 2916/4885RAB9A 1577/4885ALDH1A1 807/4885 |
| US-20080033175-A1 | Process for preparation of 4-amino-3-quinolinecarbonitriles | BTF3, PTMS, BCAT2 | NPC1 4868/4885RAB9A 4870/4885ALDH1A1 2093/4885 |
| US-20040204587-A1 | Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolones | DTYMK, DCK, TNK1 | NPC1 4795/4885RAB9A 3331/4885ALDH1A1 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.