Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL11413276 | 0.94 | TRPA1 (0.46) | TRPA1ATMALDH1A1GABRA1GABRG2 | |
| SCHEMBL357603 | 0.85 | GABRA1 (0.48) | TRPA1ATMALDH1A1GABRA1GABRG2 | |
| SCHEMBL9156005 | 0.83 | TRPA1 (0.54) | TRPA1ATMALDH1A1GABRA1MEN1 | |
| SCHEMBL29769881 | 0.83 | TRPA1 (0.54) | TRPA1ATMALDH1A1GABRA1MEN1 | |
| SCHEMBL6819372 | 0.83 | TRPA1 (0.45) | TRPA1ATMALDH1A1GABRA1GABRG2 | |
| SCHEMBL7511791 | 0.82 | TRPA1 (0.48) | TRPA1ATMALDH1A1GABRA1MEN1 | |
| SCHEMBL4551579 | 0.82 | ALDH1A1 (0.47) | TRPA1ATMALDH1A1GABRA1GABRG2 | |
| SCHEMBL8496177 | 0.81 | ALDH1A1 (0.43) | TRPA1ATMALDH1A1GABRA1GABRG2 | |
| SCHEMBL984719 | 0.81 | TRPA1 (0.52) | TRPA1ATMALDH1A1GABRA1MEN1 | |
| SCHEMBL9580544 | 0.80 | TRPA1 (0.46) | TRPA1ATMALDH1A1GABRA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510420-A | NUCLEOPHILIC GRAFTING OF PARENT POLYMER HAVING AROMATIC RINGS CONTAINING REACTIVE GROUPS | HOECHST CELANESE CORPORATION (US) | 1996-04-23 | — | — | US | claimed |
| EP-0686274-A1 | NOVEL MATRIX RESIN FOR HIGH-TEMPERATURE STABLE PHOTOIMAGEABLE COMPOSITIONS | HOECHST CELANESE CORPORATION (US) | 1995-12-13 | — | — | EP | claimed |
| WO-1994019724-A1 | NOVEL MATRIX RESIN FOR HIGH-TEMPERATURE STABLE PHOTOIMAGEABLE COMPOSITIONS | HOECHST CELANESE CORPORATION (US) | 1994-09-01 | — | — | WO | claimed |
| CN-104349848-B | Surface treatment method, surface conditioning agent and new compound | Sen Bangfu (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-104349848-A | Surface treatment method, surface treatment agent, and novel compound | MORI KUNIO | 2015-02-11 | — | — | CN | disclosed |
| CN-102187278-A | Photosensitive resin composition, method for forming silica-based coating film, and device and member having silica-based coating film | HITACHI CHEMICAL CO LTD | 2011-09-14 | — | — | CN | disclosed |
| US-7842688-B2 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2010-11-30 | — | — | US | disclosed |
| US-7790715-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-09-07 | — | — | US | disclosed |
| US-20090012055-A1 | Organic compounds | HEROLD PETER | 2009-01-08 | — | — | US | disclosed |
| EP-1961752-A2 | Piperidine Compounds | Speedel Experimenta AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-20070010511-A1 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-0485613-B1 | PROCESS FOR PARA-METHYLOLATING PHENOLIC COMPOUND | MITSUBISHI CHEM CORP (JP) | 1995-12-06 | — | — | EP | disclosed |
| CN-1111611-A | Preparation of hydroxy benzaldehyde compound | RHONE POULENC CHIMIE (FR) | 1995-11-15 | — | — | CN | disclosed |
| EP-0386639-B1 | Process for preparing para-hydroxybenzyl alcohol | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-09-28 | — | — | EP | disclosed |
| WO-1994019724-A1 | NOVEL MATRIX RESIN FOR HIGH-TEMPERATURE STABLE PHOTOIMAGEABLE COMPOSITIONS | HOECHST CELANESE CORPORATION (US) | 1994-09-01 | — | — | WO | disclosed |
| EP-0485613-A1 | PROCESS FOR PARA-METHYLOLATING PHENOLIC COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-5019656-A | Hydroxymethylation of a Phenol, Basic Catalyst, Crown Compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0386639-A1 | Process for preparing para-hydroxybenzyl alcohol | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| WO-1982000092-A1 | HAIR COLORATION METHOD AND COMPOSITION THEREFOR | KONRAD E | 1982-01-21 | — | — | WO | disclosed |
| US-4025553-A | Production of o-hydroxybenzyl alcohols | SHIONOGI & CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012055-A1 | Organic compounds | REN, ACE, ACE2 | TRPA1 186/4885ATM 4692/4885ALDH1A1 142/4885 |
| US-20070010511-A1 | Organic compounds | REN, ACE, ACE2 | TRPA1 186/4885ATM 4692/4885ALDH1A1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.