SCHEMBL30779140

SCHEMBL30779140

CNN=C(c1ccccc1)c1ccccn1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 4/20 0.65
KMT2A Q03164 4/20 0.60
MEN1 O00255 3/20 0.60
HPGD P15428 3/20 0.60
GAA P10253 2/20 0.60
ALOX12 P18054 1/20 0.60
KDM4E B2RXH2 6/20 0.56
KDM6B O15054 1/20 0.56
TET3 O43151 1/20 0.56
KDM4A O75164 1/20 0.56
KDM4B O94953 1/20 0.56
KDM5A P29375 1/20 0.56
KDM5C P41229 1/20 0.56
KDM4D Q6B0I6 1/20 0.56
TET2 Q6N021 1/20 0.56
TET1 Q8NFU7 1/20 0.56
KDM4C Q9H3R0 1/20 0.56
KDM5B Q9UGL1 1/20 0.56
HTT P42858 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30779129 1.00 AGTR1 (0.65) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL29896301 0.82 TOP2A (0.68) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL29896251 0.82 TOP2A (0.68) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL13522803 0.82 TOP2A (0.68) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL18292348 0.81 KMT2A (0.81) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL31690656 0.80 AGTR1 (0.70) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL20101080 0.80 KDM4E (0.72) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL4926318 0.80 KDM4E (0.72) AGTR1KMT2AMEN1HPGDGAA
SCHEMBL962604 0.79 ALDH1A1 (0.48) KMT2AMEN1HPGDGAAHTT
SCHEMBL15741850 0.79 AGTR1 (1.00) AGTR1KMT2AMEN1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957294-B Preparation method and application of N-heterocyclic thiosemicarbazide mixed valence copper complex 桂林医学院 2023-12-08 CN claimed
CN-114957294-B Preparation method and application of N-heterocyclic thiosemicarbazide mixed valence copper complex 桂林医学院 2023-12-08 CN disclosed