Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.68 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302837 | 1.00 | ALOX5 (0.68) | ALOX5HTR2BHTR7MAPTGAA | |
| SCHEMBL22484791 | 0.92 | ALOX5 (0.52) | ALOX5HTR2BHTR7MAPTGAA | |
| Bicarbonate SCHEMBL6265696 | 0.91 | ALOX5 (0.62) | ALOX5HTR2BHTR7MAPTGAA | |
| Phenoxazine SCHEMBL6846406 | 0.90 | ALOX5 (0.77) | ALOX5HTR2BHTR7MAPTGAA | |
| Phenoxazine SCHEMBL18770789 | 0.85 | ALOX5 (0.85) | ALOX5HTR2BHTR7MAPTGAA | |
| SCHEMBL24141298 | 0.85 | ALOX5 (0.53) | ALOX5HTR2BHTR7MAPTGAA | |
| Phenoxazine SCHEMBL29355714 | 0.82 | ALOX5 (1.00) | ALOX5HTR2BHTR7MAPTGAA | |
| Phenoxazine SCHEMBL28844098 | 0.82 | ALOX5 (1.00) | ALOX5HTR2BHTR7MAPTGAA | |
| Phenoxazine SCHEMBL6310178 | 0.82 | ALOX5 (1.00) | ALOX5HTR2BHTR7MAPTGAA | |
| Phenoxazine SCHEMBL7862 | 0.82 | ALOX5 (1.00) | ALOX5HTR2BHTR7MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024049878-A2 | BIOREDUCIBLE POLYMER AND USE THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |