Phenoxazine

Phenoxazine

SCHEMBL6846406

c1ccc2c(c1)Nc1ccccc1O2.c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 9/20 0.77
DHODH Q02127 1/20 0.47
MAPT P10636 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTR2B P41595 2/20 0.44
HTR7 P34969 1/20 0.44
GAA P10253 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
NPC1 O15118 1/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 1/20 0.44
NOX1 Q9Y5S8 1/20 0.44
LMNA P02545 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenoxazine SCHEMBL18770789 0.91 ALOX5 (0.85) ALOX5DHODHMAPTL3MBTL1TDP1
SCHEMBL30779382 0.90 ALOX5 (0.68) ALOX5DHODHMAPTL3MBTL1TDP1
SCHEMBL302837 0.90 ALOX5 (0.68) ALOX5DHODHMAPTL3MBTL1TDP1
Phenoxazine SCHEMBL29355714 0.88 ALOX5 (1.00) ALOX5DHODHMAPTL3MBTL1TDP1
Phenoxazine SCHEMBL28844098 0.88 ALOX5 (1.00) ALOX5DHODHMAPTL3MBTL1TDP1
Phenoxazine SCHEMBL6310178 0.88 ALOX5 (1.00) ALOX5DHODHMAPTL3MBTL1TDP1
Phenoxazine SCHEMBL7862 0.88 ALOX5 (1.00) ALOX5DHODHMAPTL3MBTL1TDP1
Phenoxazine SCHEMBL27458642 0.86 ALOX5 (0.63) ALOX5DHODHMAPTL3MBTL1TDP1
Phenoxazine SCHEMBL28263385 0.86 ALOX5 (0.57) ALOX5DHODHMAPTL3MBTL1TDP1
Phenoxazine SCHEMBL25275195 0.85 ALOX5 (0.94) ALOX5DHODHMAPTL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6770413-B1 Hydroxyphenyl copolymers and photoresists comprising same SHIPLEY COMPANY, L.L.C. 2004-08-03 US disclosed