Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063734 | 1.00 | ALOX5 (0.50) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL3814033 | 0.85 | ALOX5 (0.50) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL20607841 | 0.84 | MAOB (0.50) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL12475641 | 0.82 | CYP3A4 (0.44) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL4640614 | 0.79 | RXRA (0.53) | MAOBMRGPRX4ALOX5APMAPT | |
| SCHEMBL15477426 | 0.79 | GPR132 (0.48) | ALOX5LMNACYP1A2CYP2C19HIF1A | |
| SCHEMBL22303460 | 0.77 | ALOX5 (0.40) | ALOX5MAOBMRGPRX4NR4A2ALOX5AP | |
| SCHEMBL13412635 | 0.77 | ALOX5 (0.63) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL17024328 | 0.77 | ALOX5 (0.47) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL30628484 | 0.76 | C5AR1 (0.49) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |