Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063734 | 0.82 | ALOX5 (0.50) | ALOX5ALOX5APMAOBMRGPRX4LMNA | |
| SCHEMBL30779646 | 0.82 | ALOX5 (0.50) | ALOX5ALOX5APMAOBMRGPRX4LMNA | |
| SCHEMBL15477426 | 0.80 | GPR132 (0.48) | CYP3A4ALOX5LMNACYP1A2CYP2C19 | |
| SCHEMBL3814033 | 0.76 | ALOX5 (0.50) | ALOX5ALOX5APMAOBMRGPRX4LMNA | |
| SCHEMBL22303460 | 0.74 | ALOX5 (0.40) | CYP3A4ALOX5ALOX5APMAOBMRGPRX4 | |
| SCHEMBL4640614 | 0.71 | RXRA (0.53) | ALOX5APMAOBMRGPRX4MEN1KMT2A | |
| SCHEMBL17448841 | 0.70 | MAOB (0.50) | CYP3A4ALOX5MAOBLMNACYP1A2 | |
| SCHEMBL20607841 | 0.70 | MAOB (0.50) | ALOX5MAOBMRGPRX4LMNACYP1A2 | |
| SCHEMBL13412635 | 0.69 | ALOX5 (0.63) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL17024328 | 0.69 | ALOX5 (0.47) | CYP3A4ALOX5MAOBMRGPRX4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| EP-2673261-B1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-12-16 | — | — | EP | disclosed |
| EP-2673261-B1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-12-16 | — | — | EP | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| EP-2673261-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | Pierre Fabre Dermo-Cosmétique (FR) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107421-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | NQO1, SQOR, CBR1 | CYP3A4 219/4885LTA4H 572/4885MAPK14 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.