Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429270 | 0.91 | SLC6A5 (0.47) | SLC6A5ITGB3ITGA2BFAAH | |
| SCHEMBL16432430 | 0.91 | SLC6A5 (0.47) | SLC6A5ITGB3ITGA2BFAAH | |
| SCHEMBL29429319 | 0.91 | SLC6A5 (0.47) | SLC6A5ITGB3ITGA2BFAAH | |
| SCHEMBL16432431 | 0.91 | SLC6A5 (0.47) | SLC6A5ITGB3ITGA2BFAAH | |
| SCHEMBL29429271 | 0.91 | SLC6A5 (0.47) | SLC6A5ITGB3ITGA2BFAAH | |
| SCHEMBL19051472 | 0.87 | SLC6A5 (0.39) | SLC6A5ITGB3ITGA2B | |
| SCHEMBL14167626 | 0.86 | NOD1 (0.43) | SLC6A5FOLH1 | |
| SCHEMBL28167878 | 0.86 | BACE1 (0.39) | — | |
| SCHEMBL29630564 | 0.85 | SLC15A2 (0.43) | — | |
| SCHEMBL29165756 | 0.85 | CCKAR (0.36) | CCKARCCKBROPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021186-A1 | Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2026-01-22 | — | — | US | disclosed |
| EP-4565325-A2 | FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119855613-A | Fatty acid-D-amino acid peptide conjugates as anaplerotic compounds for the treatment of hyperuricemia, methylmalonic urine disorder and energy metabolism disorders | 匹兹堡大学高等教育联邦体系 | 2025-04-18 | — | — | CN | disclosed |
| WO-2024030367-A2 | FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021186-A1 | Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders | HADHB, HADHA, HADH | SLC6A5 744/4885FOLH1 271/4885CCKAR 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.